Mathematics Biophysics and Molecular Biosciences

Mathematical Biophysics and Molecular Biosciences will bring together researchers from mathematics, chemistry, biochemistry, biophysics, and molecular biology to explore new ways to bridge these diverse disciplines, and to facilitate the use of mathematics to solve open problems at the forefront of the biophysics and molecular biosciences.

The workshop will cover a wide range of topics in mathematical modeling of biomolecular structure, function, dynamics and transport, and their applications to specific research problems. Example topics are Differential geometry based multiscale models, topological simplification of biomolecules, knot theory of DNA, RNA and proteins, Implicit solvation models; Poisson-Boltzmann equation; Generalized Born models; Polarizable continuum models; Integral equation models; Density functional methods; Poisson-Nernst-Planck equations; Electroelastic models; Fluid-electro-elastic models; Micro-macro models; Continuum-discrete models; Microfluidics; Biomolecular transport; Multiscale Brownian dynamics; Electrohydrodynamics; Electrokinetics; Quantum mechanics, Molecular mechanics, and Coarse-grained models. Emphasis will be placed on the application of the aforementioned models, theories and methods to DNA packing, DNA-protein interaction, protein-protein interaction, gap junction dynamics, ion channel dynamics, ionic transport in nanopore membranes, solvation analysis, man-made nanopores, rational drug design, drug discovery and delivery, macromolecular self assembly and dynamics of molecular motors.


Benzhuo LuInstitute of Computational Mathematics, CAS
Guowei WeiMichigan State University, USA